Linking Genomic and Metabolomic Natural Variation Uncovers Nematode Pheromone Biosynthesis

In the nematodes Caenorhabditis elegans and Pristionchus pacificus, a modular library of small molecules control behavior, lifespan, and development. However, little is known about the final steps of their biosynthesis, in which diverse building blocks from primary metabolism are attached to glycosi...

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Published in:Cell Chem Biol
Main Authors: Falcke, Jan M., Bose, Neelanjan, Artyukhin, Alexander B., Rödelsperger, Christian, Markov, Gabriel V., Yim, Joshua J., Grimm, Dominik, Claassen, Marc H., Panda, Oishika, Baccile, Joshua A., Zhang, Ying K., Le, Henry. H., Jolic, Dino, Schroeder, Frank C., Sommer, Ralf J.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014897/
https://ncbi.nlm.nih.gov/pubmed/29779955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.04.004
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