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Opportunities and challenges in building a spatiotemporal multi-scale model of the human pancreatic β-cell

The construction of a predictive model of an entire eukaryotic cell that describes its dynamic structure from atomic to cellular scales is a grand challenge at the intersection of biology, chemistry, physics, and computer science. Having such a model will open new dimensions in biological research a...

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Detalhes bibliográficos
Publicado no:Cell
Principais autores: Singla, Jitin, McClary, Kyle M., White, Kate L., Alber, Frank, Sali, Andrej, Stevens, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014618/
https://ncbi.nlm.nih.gov/pubmed/29570991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.014
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