Immunohistochemical expression of proinflammatory enzyme COX-2 and p53 in ulcerative colitis and its associated dysplasia and colorectal carcinoma

BACKGROUND/AIM: Ulcerative colitis (UC) patients are at increased risk for colorectal carcinoma (CRC). It is suggested that cyclooxygenase-2 (COX-2) plays a role in sporadic CRC. The p53 gene is a tumor-suppressor gene and the most frequent site of genetic alteration found in human cancer. The aim o...

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Dettagli Bibliografici
Pubblicato in:J Microsc Ultrastruct
Autori principali: Elmashad, Nehal Mohamed, Ziada, Dina H., Hasby, Eiman A., Mohamed, Abd el motaleb
Natura: Artigo
Lingua:Inglês
Pubblicazione: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014256/
https://ncbi.nlm.nih.gov/pubmed/30023227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmau.2016.03.003
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