Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells

BACKGROUND: Quinalizarin (1,2,5,8-tetrahydroxyanthraquinone) exhibits potentially useful anticancer effects by inducing apoptosis in several types of cancer, but its underlying mechanism of action remains unknown. The present study examined the effects of quinalizarin on the induction of cell cycle...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Meng, Ling-Qi, Wang, Yue, Luo, Ying-Hua, Piao, Xian-Ji, Liu, Chang, Zhang, Yi, Wang, Jia-Ru, Wang, Hao, Xu, Wan-Ting, Liu, Yang, Wu, Yi-Qin, Sun, Hu-Nan, Han, Ying-Hao, Jin, Mei-Hua, Shen, Gui-Nan, Fang, Nan-Zhu, Jin, Cheng-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Lab/In Vitro Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014151/
https://ncbi.nlm.nih.gov/pubmed/29860266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.907163
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