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Differential effects of zinc binding on structured and disordered regions in the multidomain STIL protein
Binding of metal ions is an important regulatory mechanism in proteins. Specifically, Zn(2+) binding to disordered regions commonly induces a disorder to order transition and gain of structure or oligomerization. Here we show that simultaneous binding of Zn(2+) ions has different effects on structur...
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| Gepubliceerd in: | Chem Sci |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Royal Society of Chemistry
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6014068/ https://ncbi.nlm.nih.gov/pubmed/30155058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00115g |
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