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Cationic pillar[6]arene/ATP host–guest recognition: selectivity, inhibition of ATP hydrolysis, and application in multidrug resistance treatment

Due to the differences in the cavity size of the hosts and the charge and length of the guests, a cationic water-soluble pillar[6]arene (WP6) selectively complexes with ATP to form a stable 1 : 1 inclusion complex WP6⊃ATP. This host–guest complexation was utilized to efficiently inhibit the hydrolys...

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Опубликовано в: :Chem Sci
Главные авторы: Yu, Guocan, Zhou, Jiong, Shen, Jie, Tang, Guping, Huang, Feihe
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013913/
https://ncbi.nlm.nih.gov/pubmed/30155051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00531d
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