Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents

Somatic mutations contribute to the heterogeneous prognosis of chronic myelomonocytic leukemia (CMML). Hypomethylating agents (HMAs) are active in CMML, but analyses of small series failed to identify mutations predicting response or survival. We analyzed a retrospective multi-center cohort of 174 C...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Duchmann, Matthieu, Yalniz, Fevzi F., Sanna, Alessandro, Sallman, David, Coombs, Catherine C., Renneville, Aline, Kosmider, Olivier, Braun, Thorsten, Platzbecker, Uwe, Willems, Lise, Adès, Lionel, Fontenay, Michaela, Rampal, Raajit, Padron, Eric, Droin, Nathalie, Preudhomme, Claude, Santini, Valeria, Patnaik, Mrinal M., Fenaux, Pierre, Solary, Eric, Itzykson, Raphael
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013781/
https://ncbi.nlm.nih.gov/pubmed/29728305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.018
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