Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents

Somatic mutations contribute to the heterogeneous prognosis of chronic myelomonocytic leukemia (CMML). Hypomethylating agents (HMAs) are active in CMML, but analyses of small series failed to identify mutations predicting response or survival. We analyzed a retrospective multi-center cohort of 174 C...

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Publicado en:EBioMedicine
Autores principales: Duchmann, Matthieu, Yalniz, Fevzi F., Sanna, Alessandro, Sallman, David, Coombs, Catherine C., Renneville, Aline, Kosmider, Olivier, Braun, Thorsten, Platzbecker, Uwe, Willems, Lise, Adès, Lionel, Fontenay, Michaela, Rampal, Raajit, Padron, Eric, Droin, Nathalie, Preudhomme, Claude, Santini, Valeria, Patnaik, Mrinal M., Fenaux, Pierre, Solary, Eric, Itzykson, Raphael
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013781/
https://ncbi.nlm.nih.gov/pubmed/29728305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.018
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