Integrative (epi) Genomic Analysis to Predict Response to Androgen-Deprivation Therapy in Prostate Cancer

Therapeutic resistance is a central problem in clinical oncology. We have developed a systematic genome-wide computational methodology to allow prioritization of patients with favorable and poor therapeutic response. Our method, which integrates DNA methylation and mRNA expression data, uncovered a...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Panja, Sukanya, Hayati, Sheida, Epsi, Nusrat J., Parrott, James Scott, Mitrofanova, Antonina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013754/
https://ncbi.nlm.nih.gov/pubmed/29685789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.007
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