T Cell-Independent Gamma Interferon and B Cells Cooperate To Prevent Mortality Associated with Disseminated Chlamydia muridarum Genital Tract Infection

CD4 T cells and antibody are required for optimal acquired immunity to Chlamydia muridarum genital tract infection, and T cell-mediated gamma interferon (IFN-γ) production is necessary to clear infection in the absence of humoral immunity. However, the role of T cell-independent immune responses dur...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Poston, Taylor B., O'Connell, Catherine M., Girardi, Jenna, Sullivan, Jeanne E., Nagarajan, Uma M., Marinov, Anthony, Scurlock, Amy M., Darville, Toni
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013674/
https://ncbi.nlm.nih.gov/pubmed/29661927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00143-18
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