Glucan Binding Protein C of Streptococcus mutans Mediates both Sucrose-Independent and Sucrose-Dependent Adherence

The high-resolution structure of glucan binding protein C (GbpC) at 1.14 Å, a sucrose-dependent virulence factor of the dental caries pathogen Streptococcus mutans, has been determined. GbpC shares not only structural similarities with the V regions of AgI/II and SspB but also functional adherence t...

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Foilsithe in:Infect Immun
Main Authors: Mieher, Joshua L., Larson, Matthew R., Schormann, Norbert, Purushotham, Sangeetha, Wu, Ren, Rajashankar, Kanagalaghatta R., Wu, Hui, Deivanayagam, Champion
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2018
Ábhair:
Molecular Pathogenesis
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013656/
https://ncbi.nlm.nih.gov/pubmed/29685986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00146-18
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