Differentiation-Dependent Regulation of Human Endogenous Retrovirus K Sequences and Neighboring Genes in Germ Cell Tumor Cells

Under physiological conditions, most human endogenous retroviruses (HERVs) are transcriptionally silent. However, re-activation of HERVs is observed under pathological conditions like inflammation or cancer. In addition to expression of HERV sequences, an impact of HERV-loci on expression of adjacen...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Mueller, Thomas, Hantsch, Claudia, Volkmer, Ines, Staege, Martin S.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013571/
https://ncbi.nlm.nih.gov/pubmed/29963023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01253
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