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A New Role for Estrogen Receptor α in Cell Proliferation and Cancer: Activating the Anticipatory Unfolded Protein Response

Cells react to a variety of stresses, including accumulation of unfolded or misfolded protein, by activating the endoplasmic reticulum (EnR) stress sensor, the unfolded protein response (UPR). The UPR is highly conserved and plays a key role in the maintenance of protein folding quality control and...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Livezey, Mara, Kim, Ji Eun, Shapiro, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013567/
https://ncbi.nlm.nih.gov/pubmed/29963013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00325
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