Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis

A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 protein formulated with alum protected women <40 years old from recurrent vulvovaginal candidiasis (RVVC). We investigated the potential use of anti-Als3p sera as surrogate marker of NDV-3A efficacy. Pre...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Uppuluri, Priya, Singh, Shakti, Alqarihi, Abdullah, Schmidt, Clint S., Hennessey, John P., Yeaman, Michael R., Filler, Scott G., Edwards, John E., Ibrahim, Ashraf S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013566/
https://ncbi.nlm.nih.gov/pubmed/29963049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01349
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