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A role for frequenin, a Ca(2+)-binding protein, as a regulator of Kv4 K(+)-currents

Frequenin, a Ca(2+)-binding protein, has previously been implicated in the regulation of neurotransmission, possibly by affecting ion channel function. Here, we provide direct evidence that frequenin is a potent and specific modulator of Kv4 channels, the principal molecular components of subthresho...

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Autors principals: Nakamura, Tomoe Y., Pountney, David J., Ozaita, Ander, Nandi, Sumon, Ueda, Stefanie, Rudy, Bernardo, Coetzee, William A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC60135/
https://ncbi.nlm.nih.gov/pubmed/11606724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221168498
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