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Autoimmune disease associated IFIH1 single nucleotide polymorphism related with IL-18 serum levels in Chinese systemic lupus erythematosus patients

Systemic lupus erythematosus (SLE) has heterogeneous clinical manifestations. IFIH1 (interferon induced with helicase C domain 1) as one of antiviral helicase genes mediating type I interferon production, plays an essential role in the pathogenesis of SLE. The gene variants in IFIH1 could abnormally...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Junlong, Liu, Xinle, Meng, Yanming, Wu, Hengxu, Wu, Yongkang, Yang, Bin, Wang, Lanlan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013496/
https://ncbi.nlm.nih.gov/pubmed/29930297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27782-7
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