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Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region

The repressive activity of ancestral histone-like proteins helps integrate transcription of foreign genes with discrepant AT content into existing regulatory networks. Our investigations indicate that the AT-rich discriminator region located between the −10 promoter element and the transcription sta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tapscott, Timothy, Kim, Ju-Sim, Crawford, Matthew A., Fitzsimmons, Liam, Liu, Lin, Jones-Carson, Jessica, Vázquez-Torres, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013443/
https://ncbi.nlm.nih.gov/pubmed/29930310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27780-9
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