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Harnessing post-translational modifications for next generation HIV immunogens

The extensive post-translational modifications of the envelope spikes of the human immunodeficiency virus (HIV) present considerable challenges and opportunities for HIV vaccine design. These oligomeric glycoproteins typically have over thirty disulphide bonds, around a hundred N-linked glycosylatio...

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Publicado en:Biochem Soc Trans
Autores principales: Allen, Joel D., Sanders, Rogier W., Doores, Katie J., Crispin, Max
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013407/
https://ncbi.nlm.nih.gov/pubmed/29784645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170394
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