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Role of p42/p44 mitogen-activated-protein kinase and p21(waf1/cip1) in the regulation of vascular smooth muscle cell proliferation by nitric oxide

The purpose of this study was to determine the involvement of the p42/p44 mitogen-activated protein kinase (MAPK) pathway and induction of p21(waf1/cip1) in the antiproliferative effects of nitric oxide (NO) on rat aortic smooth muscle cells (RASMC). NO, like α-difluoromethylornithine (DFMO), interf...

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Detalhes bibliográficos
Main Authors: Bauer, Philip M., Buga, Georgette M., Ignarro, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60134/
https://ncbi.nlm.nih.gov/pubmed/11592976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211443198
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