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Aging and lymphocyte changes by immunomodulatory therapies impact PML risk in multiple sclerosis patients

New potent immunomodulatory therapies for multiple sclerosis (MS) are associated with increased risk for progressive multifocal leukoencephalopathy (PML). It is unclear why a subset of treated patients develops PML, but patient age has emerged as an important risk factor. PML is caused by the JC vir...

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Detalhes bibliográficos
Publicado no:Mult Scler
Main Authors: Mills, Elizabeth A., Mao-Draayer, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013383/
https://ncbi.nlm.nih.gov/pubmed/29774781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458518775550
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