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The keratin 16 null phenotype is modestly impacted by genetic strain background in mice
The type I intermediate filament keratin 16 (K16) is constitutively expressed in ectoderm-derived appendages and is inducibly expressed in the epidermis upon barrier-compromising challenges. Dominantly acting missense alleles in KRT16 are causative for pachyonychia congenita (PC), a genodermatosis i...
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| Publicado no: | Exp Dermatol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013353/ https://ncbi.nlm.nih.gov/pubmed/29406601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13509 |
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