Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN), or NAD itself. We provide evidence that murin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Davila, Antonio, Liu, Ling, Chellappa, Karthikeyani, Redpath, Philip, Nakamaru-Ogiso, Eiko, Paolella, Lauren M, Zhang, Zhigang, Migaud, Marie E, Rabinowitz, Joshua D, Baur, Joseph A
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2018
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013257/
https://ncbi.nlm.nih.gov/pubmed/29893687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33246
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