Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN), or NAD itself. We provide evidence that murin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Davila, Antonio, Liu, Ling, Chellappa, Karthikeyani, Redpath, Philip, Nakamaru-Ogiso, Eiko, Paolella, Lauren M, Zhang, Zhigang, Migaud, Marie E, Rabinowitz, Joshua D, Baur, Joseph A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013257/
https://ncbi.nlm.nih.gov/pubmed/29893687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33246
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