The Ubx Polycomb response element bypasses an unpaired Fab-8 insulator via cis transvection in Drosophila

Chromatin insulators or boundary elements protect genes from regulatory activities from neighboring genes or chromatin domains. In the Drosophila Abdominal-B (Abd-B) locus, the deletion of such elements, such as Frontabdominal-7 (Fab-7) or Fab-8 led to dominant gain of function phenotypes, presumabl...

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Udgivet i:PLoS One
Main Authors: Lu, Danfeng, Li, Zhuoran, Li, Lingling, Yang, Liping, Chen, Guijun, Yang, Deying, Zhang, Yue, Singh, Vikrant, Smith, Sheryl, Xiao, Yu, Wang, Erlin, Ye, Yunshuang, Zhang, Wei, Zhou, Lei, Rong, Yikang, Zhou, Jumin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013190/
https://ncbi.nlm.nih.gov/pubmed/29928011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199353
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