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Evaluation of sequence variability in HIV-1 gp41 C-peptide helix-grafted proteins
Many therapeutically-relevant protein-protein interactions (PPIs) have been reported that feature a helix and helix-binding cleft at the interface. Given this, different approaches to disrupting such PPIs have been developed. While short peptides (<15 amino acids) typically do not fold into a sta...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013034/ https://ncbi.nlm.nih.gov/pubmed/28811070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.07.064 |
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