LGG-25. NOVEL FGFR2 FUSIONS DRIVE ONCOGENESIS VIA MAPK AND PI3K/mTOR PATHWAY ACTIVATION IN DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMORS

Dysembryoplastic neuroepithelial tumor (DNT) is a benign glioneuronal neoplasm classified by the 2016 WHO under the mixed neuronal-glial tumors. Compared to other low-grade neuroepithelial tumors (LGNTs) in this category, the genetic profile of DNTs is poorly understood. DNTs have been shown to exhi...

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Опубликовано в: :Neuro Oncol
Главные авторы: Jain, Payal, Surrey, Lea, Straka, Joshua, Luo, Minjie, Resnick, Adam C, Storm, Phillip B, Santi, Mariarita, Li, Marilyn, Waanders, Angela J
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012919/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.366
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