DIPG-64. REST MODULATES NEOVASCULATURE VIA REGULATION OF GREMLIN EXPRESSION IN DIFFUSE INTRINSIC PONTINE GLIOMA

Children with diffuse intrinsic pontine glioma (DIPG) have an extremely poor survival. This underscores the desperate need for novel, biology-driven therapies. Here, we investigated the involvement of RE1 Silencing Transcription Factor (REST), a chromatin remodeler and regulator of brain development...

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Publicado no:Neuro Oncol
Main Authors: Shaik, Shavali, Kennis, Bridget, Maegawa, Shinji, Schadler, Keri, Yanwen, Yang, Callegari, Keri, Lulla, Rishi, Goldman, Stewart, Nazarian, Javad, Rajaram, Veena, Fangusaro, Jason, Gopalakrishnan, Vidya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012861/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.157
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