HGG-33. PATIENT DERIVED CELL LINES TO STUDY ATRX AND ALT IN PEDIATRIC BRAIN TUMORS

BACKGROUND: All cancers acquire a mechanism of telomere maintenance (TMM) for genomic stability and unlimited replicative potential. Some cancers, including a subset of pediatric brain tumors, use the TMM of alternative lengthening of telomeres (ALT). However, there are few cancer cell lines with AL...

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Published in:Neuro Oncol
Main Authors: Ijaz, Heba, Dilley, Robert, Koptra, Mateusz, Garcia, Gonzalo, Zhu, Yuankun, Zhang, Bo, Baubet, Valerie, Mason, Jennifer, Resnick, Adam, Gaonkar, Krutika, Waanders, Angela, Raman, Pichai, Greenberg, Roger, Cole, Kristina
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012796/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.305
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