Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications

We developed a potentially novel and robust antibody discovery methodology, termed selection of phage-displayed accessible recombinant targeted antibodies (SPARTA). This combines an in vitro screening step of a naive human antibody library against known tumor targets, with in vivo selections based o...

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Detalles Bibliográficos
Publicado en:JCI Insight
Autores principales: D’Angelo, Sara, Staquicini, Fernanda I., Ferrara, Fortunato, Staquicini, Daniela I., Sharma, Geetanjali, Tarleton, Christy A., Nguyen, Huynh, Naranjo, Leslie A., Sidman, Richard L., Arap, Wadih, Bradbury, Andrew R.M., Pasqualini, Renata
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2018
Materias:
Technical Advance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012512/
https://ncbi.nlm.nih.gov/pubmed/29720567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98305
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