Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis

In response to collagen stimulation, platelets use a coordinated system of fluid entry to undergo membrane ballooning, procoagulant spreading, and microvesiculation. We hypothesized that water entry was mediated by the water channel aquaporin-1 (AQP1) and aimed to determine its role in the platelet...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Agbani, Ejaife O., Williams, Christopher M., Li, Yong, van den Bosch, Marion T.J., Moore, Samantha F., Mauroux, Adele, Hodgson, Lorna, Verkman, Alan S., Hers, Ingeborg, Poole, Alastair W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012506/
https://ncbi.nlm.nih.gov/pubmed/29769447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99062
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