DIPG-38. ID1 EXPRESSION CORRELATES WITH H3F3A K27M MUTATION AND EXTRA-PONTINE INVASION IN DIPG

ID1 regulates transcription by interacting with bHLH transcription factors and previous work has shown that over-expression of the recurrent DIPG H3F3A K27M and ACVR1 mutations in cultured astrocytes lead to an increase in ID1 expression; this has not been validated in human DIPG. DNA (exome)/RNA se...

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Published in:Neuro Oncol
Main Authors: Stallard, Stefanie, Siddaway, Robert, Miklja, Zachary, Mullan, Brendan, Garcia, Taylor, Zamler, Daniel, Kasaian, Katayoon, Cao, Xuhong, Anderson, Bailey, Hervey-Jumper, Shawn, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Venneti, Sriram, Hawkins, Cynthia, Koschmann, Carl
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012227/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.131
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