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NFM-08. SAFETY AND EFFICACY OF TRAMETINIB IN THE MANAGEMENT OF CHILDREN WITH RASOPATHIES
BACKGROUND: There is emerging evidence regarding the efficacy of agents targeting the MAPK pathway in children with RASopathies. We report our experience with the use of trametinib, a MEK inhibitor, in this population. METHODS: Three patients with neurofibromatosis type 1 (NF-1) and plexiform neurof...
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| Publié dans: | Neuro Oncol |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012195/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.516 |
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