NFM-08. SAFETY AND EFFICACY OF TRAMETINIB IN THE MANAGEMENT OF CHILDREN WITH RASOPATHIES

BACKGROUND: There is emerging evidence regarding the efficacy of agents targeting the MAPK pathway in children with RASopathies. We report our experience with the use of trametinib, a MEK inhibitor, in this population. METHODS: Three patients with neurofibromatosis type 1 (NF-1) and plexiform neurof...

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Publié dans:Neuro Oncol
Auteurs principaux: Bavle, Abhishek, Choudhry, Farooq, Gavula, Theresa, Shah, Rikin, Ruiz-Elizalde, Alejandro, Taylor, Ashley, Gross, Naina, Peterson, Jo Elle, Fung, Kar-Ming, McNall-Knapp, Rene
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012195/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.516
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