HGG-21. IMAGING AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF H3 G34R-MUTANT GLIOMAS -A REPORT OF TWO CASES

Missense somatic mutations affecting histone H3.1 and H3.3 proteins are common in diffuse intrinsic pontine and thalamic gliomas and in a subset of cerebral hemispheric gliomas. The K27M mutation in histone H3.3 (H3F3A) and H3.1 (HIST1H3B/C) are defined as a new entity and named “diffuse midline gli...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Onishi, Shumpei, Karlowee, Vega, Nakano, Yoshiko, Kolakshyapati, Manish, Takayasu, Takeshi, Takano, Motoki, Amatya, Vishwa Jeet, Takeshima, Yukio, Ichimura, Koichi, Sugiyama, Kazuhiko, Kurisu, Kaoru, Yamasaki, Fumiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012006/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.293
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