MBRS-63. CCR2+ HEMATOPOIETIC STEM CELLS OVERCOME TREATMENT RESISTANCE TO PD-1 IN MEDULLOBLASTOMA

INTRODUCTION: We have previously reported that different medulloblastoma models have different responsiveness to checkpoint blockade including anti-PD-1. In a preclinical model of molecular subtype sonic hedgehog (Shh) medulloblastoma (Ptc) that is completely resistant to PD-1 blockade alone, we hav...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Flores, Catherine, Wildes, Tyler, Drake, Jeffrey, Abraham, Rebecca, Mitchell, Duane
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012005/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.507
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