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MBRS-63. CCR2+ HEMATOPOIETIC STEM CELLS OVERCOME TREATMENT RESISTANCE TO PD-1 IN MEDULLOBLASTOMA
INTRODUCTION: We have previously reported that different medulloblastoma models have different responsiveness to checkpoint blockade including anti-PD-1. In a preclinical model of molecular subtype sonic hedgehog (Shh) medulloblastoma (Ptc) that is completely resistant to PD-1 blockade alone, we hav...
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Publié dans: | Neuro Oncol |
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Auteurs principaux: | , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Oxford University Press
2018
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012005/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.507 |
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