Naltrexone alters alcohol self-administration behaviors and hypothalamic-pituitary-adrenal axis activity in a sex-dependent manner in rats

BACKGROUND: The mu-opioid antagonist, naltrexone (NTX), is a FDA-approved treatment for alcohol use disorder (AUD); however, the data on whether it differentially affects males vs. females are mixed. NTX increases hypothalamic-pituitary-adrenal (HPA) axis activity that associates with subjective res...

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I publikationen:Pharmacol Biochem Behav
Huvudupphovsmän: Nieto, Steven J., Quave, Cana B., Kosten, Therese A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011835/
https://ncbi.nlm.nih.gov/pubmed/29486222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2018.02.003
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