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Target achievement and cardiovascular event rates with Lomitapide in homozygous Familial Hypercholesterolaemia

BACKGROUND: Homozygous familial hypercholesterolaemia (HoFH) is characterized by a markedly increased risk of premature cardiovascular (CV) events and cardiac death. Lomitapide reduces low-density lipoprotein cholesterol (LDL-C) levels; however, the probable impact on LDL-C goals and CV events is un...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Blom, Dirk J., Cuchel, Marina, Ager, Miranda, Phillips, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011273/
https://ncbi.nlm.nih.gov/pubmed/29925433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-018-0841-3
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