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Characterization of Atherosclerosis Formation in a Murine Model of Type IIa Human Familial Hypercholesterolemia
A murine genetic model of LDL-cholesterol- (LDL-C-) driven atherosclerosis, based on complete deficiencies of both the LDL-receptor (Ldlr(−/−)) and key catalytic component of an apolipoprotein B-edisome complex (Apobec1(−/−)), which converts apoB-100 to apoB-48, has been extensively characterized. T...
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| Publicado en: | Biomed Res Int |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Hindawi
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6011105/ https://ncbi.nlm.nih.gov/pubmed/29977908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1878964 |
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