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MicroRNA-206 Downregulation Improves Therapeutic Gene Expression and Motor Function in mdx Mice
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disorder caused by a mutation in the dystrophin gene. Numerous gene therapies have been developed to replace or repair the defective dystrophin gene; however, these treatments cannot restore the full-length protein or completely resolve dy...
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| Publicado no: | Mol Ther Nucleic Acids |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6011022/ https://ncbi.nlm.nih.gov/pubmed/30195767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.05.011 |
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