DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells

Preclinical models indicate that DNA damage induces type I interferon (IFN), which is crucial for the induction of an anti-tumor immune response. In human cancers, however, the association between DNA damage and an immunogenic cell death (ICD), including the release and sensing of danger signals, th...

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Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Laengle, Johannes, Stift, Judith, Bilecz, Agnes, Wolf, Brigitte, Beer, Andrea, Hegedus, Balazs, Stremitzer, Stefan, Starlinger, Patrick, Tamandl, Dietmar, Pils, Dietmar, Bergmann, Michael
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010984/
https://ncbi.nlm.nih.gov/pubmed/29930723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.24699
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