Optogenetic Activation of Colon Epithelium of the Mouse Produces High-Frequency Bursting in Extrinsic Colon Afferents and Engages Visceromotor Responses

Epithelial cells of the colon provide a vital interface between the internal environment (lumen of the colon) and colon parenchyma. To examine epithelial–neuronal signaling at this interface, we analyzed mice in which channelrhodopsin (ChR2) was targeted to either TRPV1-positive afferents or to vill...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Makadia, Payal A., Najjar, Sarah A., Saloman, Jami L., Adelman, Peter, Feng, Bin, Margiotta, Joseph F., Albers, Kathryn M., Davis, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010562/
https://ncbi.nlm.nih.gov/pubmed/29789376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0837-18.2018
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