Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta)

Conservation of the genetic resources of endangered animals is crucial for future generations. The loggerhead sea turtle (Caretta caretta) is a critically endangered species, because of human hunting, hybridisation with other sea turtle species, and infectious diseases. In the present study, we esta...

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Publicado no:Sci Rep
Main Authors: Fukuda, Tomokazu, Eitsuka, Takahiro, Donai, Kenichiro, Kurita, Masanori, Saito, Tomomi, Okamoto, Hitoshi, Kinoshita, Kodzue, Katayama, Masafumi, Nitto, Hiroshi, Uchida, Takafumi, Onuma, Manabu, Sone, Hideko, Inoue-Murayama, Miho, Kiyono, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010431/
https://ncbi.nlm.nih.gov/pubmed/29925962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27271-x
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