Protective effects of a novel drug RC28-E blocking both VEGF and FGF2 on early diabetic rat retina

AIM: To investigate protective effects of a novel recombinant decoy receptor drug RC28-E on retinal damage in early diabetic rats. METHODS: The streptozotocin (STZ)-induced diabetic rats were randomly divided into 6 groups: diabetes mellitus (DM) group (saline, 3 µL/eye); RC28-E at low (0.33 µg/µL,...

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Udgivet i:Int J Ophthalmol
Main Authors: Yang, Qian-Hui, Zhang, Yan, Jiang, Jing, Wu, Mian-Mian, Han, Qian, Bo, Qi-Yu, Yu, Guang-Wei, Ru, Yu-Sha, Liu, Xun, Huang, Min, Wang, Ling, Zhang, Xiao-Min, Fang, Jian-Min, Li, Xiao-Rong
Format: Artigo
Sprog:Inglês
Udgivet: International Journal of Ophthalmology Press 2018
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010370/
https://ncbi.nlm.nih.gov/pubmed/29977804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2018.06.07
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