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Sulfonamide inhibition studies of two β-carbonic anhydrases from the ascomycete fungus Sordaria macrospora, CAS1 and CAS2

The two β-carbonic anhydrases (CAs, EC 4.2.1.1) recently cloned and purified from the ascomycete fungus Sordaria macrospora, CAS1 and CAS2, were investigated for their inhibition with a panel of 39 aromatic, heterocyclic, and aliphatic sulfonamides and one sulfamate, many of which are clinically use...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Vullo, Daniela, Lehneck, Ronny, Pöggeler, Stefanie, Supuran, Claudiu T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010127/
https://ncbi.nlm.nih.gov/pubmed/29363370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1425687
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