Structural re-positioning, in silico molecular modelling, oxidative degradation, and biological screening of linagliptin as adenosine 3 receptor (ADORA3) modulators targeting hepatocellular carcinoma

Chemical entities with structural diversity were introduced as candidates targeting adenosine receptor with different clinical activities, containing 3,7-dihydro-1H-purine-2,6-dione, especially adenosine 3 receptors (ADORA3). Our initial approach started with pharmacophore screening of ADORA3 modula...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Ayoub, Bassam M., Attia, Yasmeen M., Ahmed, Mahmoud S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010121/
https://ncbi.nlm.nih.gov/pubmed/29768061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1462801
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados