Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease

Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO(2). The present work is aimed to clone the oxdC gene in a mammalian expres...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Albert, Abhishek, Tiwari, Vidhi, Paul, Eldho, Ganesan, Divya, Ayyavu, Mahesh, Kujur, Ritu, Ponnusamy, Sasikumar, Shanmugam, Kathiresan, Saso, Luciano, Govindan Sadasivam, Selvam
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010120/
https://ncbi.nlm.nih.gov/pubmed/28118755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1256884
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