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Benzo[g]quinazolin-based scaffold derivatives as dual EGFR/HER2 inhibitors
Targeting EGFR has proven to be beneficial in the treatment of several types of solid tumours. So, a series of novel 2-(4-oxo-3-(4-sulfamoylphenyl)-3,4-dihydrobenzo[g]quinazolin-2-ylthio)-N-substituted acetamide 5–19 were synthesised from the starting material 4-(2-mercapto-4-oxobenzo[g]quinazolin-3...
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| Опубликовано в: : | J Enzyme Inhib Med Chem |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010119/ https://ncbi.nlm.nih.gov/pubmed/29098904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1389922 |
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