Dioxygen, an unexpected carbonic anhydrase ligand

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, grouped into seven different classes, which catalyze the reaction of CO(2) hydration to bicarbonate and protons. All of the fifteen human isoforms reported to date belong to the α-class and contain zinc as a cofactor. The structure...

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Detalles Bibliográficos
Publicado en:J Enzyme Inhib Med Chem
Autores principales: Ferraroni, Marta, Gaspari, Roberto, Scozzafava, Andrea, Cavalli, Andrea, Supuran, Claudiu T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010096/
https://ncbi.nlm.nih.gov/pubmed/29806484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1475371
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