Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines

4-(3-(4-Substituted-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamides (9–16) were successfully synthesized and their chemical structures were confirmed by (1)H NMR, (13)C NMR, and HRMS spectra. Carbonic anhydrase I and II inhibitory effects of the compounds were investigated. K(i) va...

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Dades bibliogràfiques
Publicat a:J Enzyme Inhib Med Chem
Autors principals: Gul, Halise Inci, Mete, Ebru, Taslimi, Parham, Gulcin, Ilhami, Supuran, Claudiu T.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010057/
https://ncbi.nlm.nih.gov/pubmed/27774818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1244533
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