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Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia
BACKGROUND: Vimentin (VIM) is a type III intermediate filament that maintains cell integrity, and is involved in cell migration, motility and adhesion. When overexpressed in solid cancers, vimentin drives epithelial to mesenchymal transition (EMT) and ultimately, metastasis. The effects of its overe...
Gardado en:
| Publicado en: | J Transl Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009962/ https://ncbi.nlm.nih.gov/pubmed/29925392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1539-y |
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