The first activation study of a δ-carbonic anhydrase: TweCAδ from the diatom Thalassiosira weissflogii is effectively activated by amines and amino acids

The activation of the δ-class carbonic anhydrase (CAs, EC 4.2.1.1) from the diatom Thalassiosira weissflogii (TweCAδ) was investigated using a panel of natural and non-natural amino acids and amines. The most effective activator of TweCAδ was d-Tyr (K(A) of 51 nM), whereas several other amino acids...

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Veröffentlicht in:J Enzyme Inhib Med Chem
Hauptverfasser: Angeli, Andrea, Alasmary, Fatmah A. S., Del Prete, Sonia, Osman, Sameh M., AlOthman, Zeid, Donald, William A., Capasso, Clemente, Supuran, Claudiu T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009927/
https://ncbi.nlm.nih.gov/pubmed/29536765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1447570
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