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Structure–activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor
Fraxamoside, a macrocyclic secoiridoid glucoside featuring a hydroxytyrosol group, was recently identified as a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout drug allopurinol. However, this activity and its considerably higher value than its derivatives ole...
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| Publicado no: | J Enzyme Inhib Med Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009875/ https://ncbi.nlm.nih.gov/pubmed/28097900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1252758 |
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