Activation studies with amines and amino acids of the β-carbonic anhydrase encoded by the Rv3273 gene from the pathogenic bacterium Mycobacterium tuberculosis

The activation of a β-class carbonic anhydrase (CAs, EC 4.2.1.1) from Mycobacterium tuberculosis, encoded by the gene Rv3273 (mtCA 3), was investigated using a panel of natural and non-natural amino acids and amines. mtCA 3 was effectively activated by D-DOPA, L-Trp, dopamine and serotonin, with K(A...

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Publicado en:J Enzyme Inhib Med Chem
Autores principales: Angeli, Andrea, Del Prete, Sonia, Osman, Sameh M., Alasmary, Fatmah A. S., AlOthman, Zeid, Donald, William A., Capasso, Clemente, Supuran, Claudiu T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009870/
https://ncbi.nlm.nih.gov/pubmed/29322836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1422250
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